Connect with us

Health

Dr Seema Mishra, of University of Hyderabad developed a possible Coronavirus Vaccine

Published

on

Dr Seema Mishra, of University of Hyderabad developed a possible Coronavirus Vaccine

Among the frightening episodes of Coronavirus, a hope is expected from the University of Hyderabad (UOH). The faculty of the Biochemistry section developed the vaccine against terrible coronavirus infection. According to a statement by you, School of Life Sciences, faculty of the Department of Biochemistry, Dr. Seema Mishra has made potential candidates of vaccine, known as T cell epitopes, overall the non-structural and structural novel coronavirus-2 proteins for testing experimentally.

These vaccine candidates are tiny peptides of Coronavirus molecules used in motivation to motivate immune response to kill cells containing these viral peptides. Using immunoinformatics policies with the software of computation, Dr. Seima Mishra has created potential epitopes to use as vaccinations to the total population.
Generally, the vaccine takes 15 years for invention, but powerful computation helps to quickly add these vaccinators in 10 days. The rank list of potential candidates vacuum is depended on how much human use cells can stop how to make them the effect of the virus.

Also Read:  After Delhi and Haryana, coronavirus epidemic declared in UP, all schools and colleges closed till 22 March 

Because there are no matches in human protein, these Corona viral epitopes do not have cross-reactivity to the cells of humans and therefore, the immune response is over viral proteins and is not for human proteins. Anyhow, these results should be experimentally tested to provide determinant evidence. The results are spread to scientific society using the platform of chemRxiv Preprint for emergency experimental tests.

The social distance is currently the best protection from not infections, and the candidate should be more work on the epitopes so that UOH states that it would take some time to lay the vaccine. “Our computational investigations have said that we offer the cost-and-time-effective framework for faster experimental tests toward efficient NCOV vaccine” it stated.
The research has spread between members of the scientific community and the University of Hyderabad has conducted the in-vitro studies to confirm the results.

Also Read:  How Does Weather Affect COVID Cases?

Continue Reading
Click to comment

Leave a Reply

Your email address will not be published. Required fields are marked *

Health

Does Tea Cure COVID-19?

Published

on

By

It is a well-known fact that improved immunity is the only way to fight against COVID-19 infection as there are no drugs or vaccines discovered to destroy the virus. Doctors have been treating coronavirus patients worldwide by improving immunity and fighting the virus. Similarly, improved immunity also helps prevent viral infection. Hence, immunity boosters have been playing a crucial role in the pandemic, as insisted by the World Health Organization (WHO).

Recently, a rumor has it that drinking tea does cure the coronavirus. It buzzes that the Chinese doctor Dr. Li Wenliang, who had warned in the initial stage of the COVID-19 epidemic, also found that tea cures the virus. Later it was observed that the tea consists of chemicals that kill the virus in the cells engineered in vitro experiments. But according to the Zhejiang Provincial Center for Disease Control and Prevention, in vitro tests are not enough to prove that tea helps in curing coronavirus.

Also Read:  Doctors advice people to get vaccinated immediately

According to research in the Indian Institute of Technology (IIT), Delhi, scientists have found that tea actually helps in treating coronavirus. They state that consuming Myrrh with tea is a potential cure as Myrrh and tea are effective in preventing the growth of an essential protein in the COVID-19 virus. These two plants have the power to reduce the strength of the virus, as concluded by the study of Kusuma School of Biological Sciences (KSBS) on fifty-one herbal plants on clones of the coronavirus protein.

However, clinical trials are required to come to a conclusion, says Prof. Ashok Kumar Patel, leader of the research, IIT.

Benefits of Green Tea

According to scientists, green tea is rich in anti-bacterial properties and also helps in controlling cholesterol and Blood Pressure (BP). Also, black tea is an excellent immunity booster.

Also Read:  How to protect yourself from the Coronavirus outbreak?

 

Continue Reading

Health

Difference Between PTSD and Other Mental Ailments

Published

on

By

Post-Traumatic Stress Disorder is the reflex action of mind against traumas in a person’s life. The trauma may be physical or sexual abuse, accidents, natural or human-made catastrophes, war combats, terrorism, loss of a loved one, or any other incident that had deeply affected the person’s psychology. It is common in people who have undergone any such disturbing events, but it is often confused with other mental ailments like depression, anxiety, substance abuse, etc.

Women are twice likely than men to develop PTSD, and children do too. Though a person may recover from PTSD at one point, he may continue to suffer from depression and anxiety for months and sometimes even years.

To treat a disorder, it is necessary that we find its origin first. So, it is essential that we identify PTSD accurately. And PTSD is often difficult to diagnose.

Also Read:  How Does Weather Affect COVID Cases?

How to Differentiate Between PTSD and Other Mental Disorders?

Overlapping symptoms is one of the primary reasons for this confusion. For instance, a person may suffer from depression and anxiety at once or depression and PTSD at once. Sometimes, the symptoms of the two different conditions may even co-exist. Consider a person who is already suffering from depression. If he/she undergoes a traumatic incident, apart from PTSD, depression deepens. Though there is no particular cause of depression, PTSD follows any traumatic events like rape, witnessing a crime, etc.

So, here is a list of common symptoms of PTSD that will help you figure out if a person is suffering from PTSD:

It is not necessary that the symptoms start showing up right after the incident. It may take months or even years after the traumatic incident.

Also Read:  How to protect yourself from the Coronavirus outbreak?

There are three significant symptoms:

  • Recurring memories of the incident that affected you, like flashbacks or over voices, nightmares and reliving the incident through theses type of physical or emotional reactions.
  • Emotional numbness and avoiding talking about the incident or anything or anyone related to it.
  • Feeling on edge, jumpy, easily scared or angered, difficulty in sleeping and concentrating.

You may be down on yourself. You shall feel:

  • Persistently negative moods
  • Hopeless, depressed,
  • Self-destructive like drinking too much alcohol or drive too fast
  • Detached from people and social interactions
  • easily startled or frightened, or you might always be on guard for danger
  • Have trouble sleeping due to fear of nightmares that make you relive the memory

Some overlapping symptoms of PTSD and other mental illnesses are Insomnia, Lack of focus, lack of interest, Irritability, Detachment from people, and the world.

Also Read:  Doctors advice people to get vaccinated immediately

If you feel or notice a person feeling the symptoms mentioned above for four weeks or longer, then it is impulsive that you consult a psychiatrist for professional advice, diagnosis, and treatment.

 

Continue Reading

Health

Researchers suspect that SARS-CoV-2 might be evolving since 2013

Published

on

By

Researchers of the University of Calgary in Canada, suspect that the novel Coronavirus (SARS-CoV-2) might be in evolution among humans since around 2013. But it might not be the same strain that is causing this COVID-19 pandemic.

Six strains of Coronavirus wereCoronavirus commonly prevalent among animals. But the seventh strain is an anonymous strain that is wreaking havoc in the form of COVID-19 and causing a global catastrophe by infecting the human population in the mass.

While scientists throughout the world are working hard to figure out the virus, its effects, origin, and cure, the World Health Assembly had passed a resolution to find the source of the strain.

There are multiple theories of origin. One, the virus got transferred from an animal to a human. Two, it was artificially developed in a laboratory in china for some medical reasons. However, studies rule out this possibility by saying the origin is natural and not human-made.

Recently, a team of researchers at the University of Calgary in Canada say that the SARS-CoV-2 might have been in circulation among humans beginning from as early as 2013. However, it would not be the same strain responsible for the pandemic. They have submitted their report at the Biorxiv, but the findings of the research have not yet been reviewed by the peers.

Also Read:  How Does Weather Affect COVID Cases?

It is upon the survival mechanism of the viruses that they keep evolving with the changes with the host organism, i.e., if the host evolves, the virus evolves too. So, when the virus jumped from an animal to human, it would nave underwent genetic modification that would produce a new strain of the same virus, only that now it is more powerful and infective. This implies the virus that had mild or no effect on the animal host may have enormous impacts on the human host. For example, the strain of the virus in the bats did not affect the bats, as their immune system was equipped to co-exist with the virus. However, once it jumped hosts, we obviously tend to fall sick.

What does the Canadian Study say?

The study was conducted by the University of Calgary in Canada between 30 December 2019 to 20 March 2020, when they collected about 479 genome sequences of the novel Coronavirus to study its phylogeny. Phylogeny is the study of the evolutionary development of the virus and its relation to other closely related viruses.

Also Read:  Coronavirus spreads through your mobile phones too!

The researchers examined the spike protein of the strain of SARS-CoV-2 and how it attaches to the receptors in the human body. This attachment of the novel Coronavirus and the receptors to the human cells determine how the virus invades the healthy tissues. They found 16 variant strains of the virus and about 11 missense mutations out of the 479 genomes. A mutation is when a single nucleotide change makes the DNA/RNA code for a different protein. Thus, some of them gave rise to a separate phylogenetic tree.

Another one of their findings included that the SARS-CoV-2 might be a combination of both bat virus and the pangolin virus. The study found that the genome of novel coronavirus matched 96 percent with that of bat virus and 90 percent with that of the pangolin virus. They predict that this variant might have developed due to a co-infection in the host.

Also Read:  Karnataka Police Planning to Seize all Vehicles Except Those of the Essential Service Providers

To trace the origin of this novel Coronavirus, the researchers created an ancestral sequence of the receptor-binding domain (RBD) of the spike protein of SARS-CoV-2 and labeled it N1. RBD is the part of the spike protein that actually binds with the receptor. The animal virus, which is the common ancestor, was labeled N0.

With what they discovered in the experiment, the scientists concluded that the binding affinity of SARS-CoV-2 might not be a determinant of its infectivity. Further, they predict that there should be some other factors that increased their infectivity in humans. The main conclusion is that the ancestral virus could have been infecting humans too, but with unnoticeable symptoms.

 

Continue Reading

Trending